Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 7/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23329957 | 0.88 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| SCHEMBL20803992 | 0.81 | ASIC3 (0.49) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| SCHEMBL19525658 | 0.81 | PNMT (0.43) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| SCHEMBL7921103 | 0.80 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| SCHEMBL19642623 | 0.79 | ITGB3 (0.42) | PNMT | |
| SCHEMBL26141680 | 0.77 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| SCHEMBL4678560 | 0.76 | ITGB3 (0.43) | PNMT | |
| Hydrochloric Acid SCHEMBL30041859 | 0.76 | PNMT (0.53) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| Hydrochloric Acid SCHEMBL23706229 | 0.76 | PNMT (0.53) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| SCHEMBL22543786 | 0.75 | PNMT (0.49) | PNMTADRA2AADRA2BADRA2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079759-A1 | BICYCLIC LACTAM FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-07-03 | — | — | WO | disclosed |