SCHEMBL8170347

SCHEMBL8170347

CCO[CH]NC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41
EPHX2 P34913 5/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 2/20 0.35
LMNA P02545 2/20 0.34
THRB P10828 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27499677 0.72 GRIN2D (0.41) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL1674746 0.69 LMNA (0.54) KMT2AMEN1EPHX2SMN1; SMN2ALDH1A1
SCHEMBL5804293 0.69 GRIN2D (0.52) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL14313766 0.68 GRIN2D (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL8170349 0.67 EPHX2 (0.47) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL3947821 0.65 LMNA (0.35) KMT2AMEN1ALDH1A1LMNA
SCHEMBL20609248 0.64 EPHX2 (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3085164 0.64 EPHX2 (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL812583 0.64 EPHX2 (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1548214 0.64 GRIN2D (0.54) KMT2AMEN1GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1243050-C Films made from substantially linear homogeneous olefin polymer compositions DOW CHEMICAL CO (US) 2006-02-22 CN disclosed
CN-1103358-C hot melt adhesive DOW CHEMICAL CO (US) 2003-03-19 CN disclosed
CN-1100072-C Ultra-low molecular weight ethylene polymers DOW CHEMICAL CO (US) 2003-01-29 CN disclosed
CN-1098857-C Substituted indenyl contg. metal complexes and olefin polymerization process DOW CHEMICAL CO (US) 2003-01-15 CN disclosed
CN-1267315-A Films made from substantially linear homogeneous olefin polymer compositions DOW CHEMICAL CO (US) 2000-09-20 CN disclosed
CN-1256705-A Polymer compositions having improved elongation DOW CHEMICAL CO (US) 2000-06-14 CN disclosed
EP-1003812-A1 FILMS PRODUCED FROM SUBSTANTIALLY LINEAR HOMOGENEOUS OLEFIN POLYMER COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 2000-05-31 EP disclosed
CN-1226280-A hot melt adhesive DOW CHEMICAL CO (US) 1999-08-18 CN disclosed
CN-1209816-A Ultra low molecular weight ethylene polymers DOW CHEMICAL CO (US) 1999-03-03 CN disclosed
WO-1999009096-A1 FILMS PRODUCED FROM SUBSTANTIALLY LINEAR HOMOGENEOUS OLEFIN POLYMER COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1999-02-25 WO disclosed
CN-1200739-A easily supported metal complexes DOW CHEMICAL CO (US) 1998-12-02 CN disclosed