Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244877 | 0.72 | HTT (0.48) | LMNAALDH1A1GLACNR2NPSR1 | |
| SCHEMBL3250932 | 0.71 | ALDH1A1 (0.52) | LMNAALDH1A1GLACNR2NPSR1 | |
| SCHEMBL7702205 | 0.71 | ALDH1A1 (0.59) | LMNAALDH1A1GLAKDM4EHTT | |
| SCHEMBL15020936 | 0.70 | LMNA (0.43) | LMNAALDH1A1GLACNR2KDM4E | |
| SCHEMBL8170347 | 0.69 | KMT2A (0.44) | LMNAALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL23220249 | 0.68 | THRB (0.63) | LMNAALDH1A1GLANPSR1KDM4E | |
| SCHEMBL2841738 | 0.68 | THRB (0.63) | LMNAALDH1A1GLANPSR1KDM4E | |
| SCHEMBL1073543 | 0.67 | LMNA (0.59) | LMNAALDH1A1CNR2NPSR1KDM4E | |
| SCHEMBL13527520 | 0.67 | GLA (0.61) | LMNAALDH1A1GLANPSR1KDM4E | |
| SCHEMBL3712266 | 0.67 | LMNA (0.58) | LMNAALDH1A1CNR2NPSR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42276-E1 | High melt strength polymers and method of making same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-04-05 | — | — | US | disclosed |
| EP-1003812-B1 | FILMS PRODUCED FROM SUBSTANTIALLY LINEAR HOMOGENEOUS OLEFIN POLYMER COMPOSITIONS | DOW GLOBAL TECHNOLOGIES INC (US) | 2005-02-09 | — | — | EP | disclosed |
| US-20050020778-A1 | High melt strength polymers and method of making same | DOW GLOBAL TECHNOLOGIES LLC | 2005-01-27 | — | — | US | disclosed |
| CN-1538977-A | Process for preparing interpolymers and products made therefrom | — | 2004-10-20 | — | — | CN | disclosed |
| CN-1527847-A | High melt strength polymers and methods of making the same | — | 2004-09-08 | — | — | CN | disclosed |
| EP-1412398-A2 | HIGH MELT STRENGTH POLYMERS AND METHOD OF MAKING SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20030088037-A1 | Method of making interpolymers and products made therefrom | THE DOW CHEMICAL COMPANY (US) | 2003-05-08 | — | — | US | disclosed |
| WO-2002100906-A1 | USE OF POLAR MONOMERS IN OLEFIN POLYMERIZATION AND POLYMERS THEREOF | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| WO-2002074816-A2 | HIGH MELT STRENGTH POLYMERS AND METHOD OF MAKING SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-09-26 | — | — | WO | disclosed |
| EP-1003812-A1 | FILMS PRODUCED FROM SUBSTANTIALLY LINEAR HOMOGENEOUS OLEFIN POLYMER COMPOSITIONS | THE DOW CHEMICAL COMPANY (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999009096-A1 | FILMS PRODUCED FROM SUBSTANTIALLY LINEAR HOMOGENEOUS OLEFIN POLYMER COMPOSITIONS | THE DOW CHEMICAL COMPANY (US) | 1999-02-25 | — | — | WO | disclosed |
| CN-1200739-A | easily supported metal complexes | DOW CHEMICAL CO (US) | 1998-12-02 | — | — | CN | disclosed |