SCHEMBL8170349

SCHEMBL8170349

CCOCNC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 8/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
GRIN3A Q8TCU5 1/20 0.44
CNR2 P34972 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1548214 0.77 GRIN2D (0.54) EPHX2KMT2AMEN1GRIN2DGRIN3B
SCHEMBL14503347 0.75 GRIN2D (0.41) EPHX2KMT2AMEN1GRIN2DGRIN3B
Water SCHEMBL21840768 0.75 GRIN2D (0.52) EPHX2KMT2AMEN1GRIN2DGRIN3B
Hydrochloric Acid SCHEMBL4433215 0.75 GRIN2D (0.52) EPHX2KMT2AMEN1GRIN2DGRIN3B
SCHEMBL60897 0.73 GRIN2D (0.48) EPHX2KMT2AMEN1GRIN2DGRIN3B
SCHEMBL3188537 0.71 GRIN2D (0.50) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL3455397 0.70 OPRK1 (0.66) EPHX2KMT2AMEN1SMN1; SMN2
SCHEMBL7430443 0.70 EPHX2 (0.52) EPHX2
SCHEMBL11922812 0.70 EPHX2 (0.49) EPHX2KMT2AGRIN2DGRIN3BGRIN1
SCHEMBL4082783 0.70 EPHX2 (0.40) EPHX2KMT2AMEN1GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1003812-A1 FILMS PRODUCED FROM SUBSTANTIALLY LINEAR HOMOGENEOUS OLEFIN POLYMER COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 2000-05-31 EP disclosed
WO-1999009096-A1 FILMS PRODUCED FROM SUBSTANTIALLY LINEAR HOMOGENEOUS OLEFIN POLYMER COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1999-02-25 WO disclosed