Methacrylic Acid

Methacrylic Acid

SCHEMBL8170359

C=C(C)C(=O)O.C=C(C)C(=O)OCCNC(C)(C)C

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.44
TSHR P16473 3/20 0.43
GAA P10253 1/20 0.39
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 5/20 0.38
POLB P06746 2/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26306 0.95 THRB (0.48) THRBTSHRGAAALDH1A1KDM4E
Fluoride SCHEMBL8582115 0.93 THRB (0.47) THRBTSHRGAAALDH1A1KDM4E
Hydrochloric Acid SCHEMBL1396466 0.93 THRB (0.47) THRBTSHRGAAALDH1A1KDM4E
Bromide SCHEMBL11526296 0.93 THRB (0.47) THRBTSHRGAAALDH1A1KDM4E
SCHEMBL8175481 0.90 ALDH1A1 (0.52) THRBTSHRGAAALDH1A1KDM4E
1,1-Dichloroethene SCHEMBL10925544 0.90 THRB (0.44) THRBTSHRGAAALDH1A1KDM4E
SCHEMBL5139727 0.89 THRB (0.42) THRBTSHRGAAALDH1A1KDM4E
Acrylic Acid SCHEMBL30601867 0.89 THRB (0.41) THRBTSHRGAAALDH1A1KDM4E
SCHEMBL6431278 0.88 THRB (0.47) THRBTSHRGAAALDH1A1KDM4E
SCHEMBL29664570 0.85 THRB (0.36) THRBTSHRGAAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113072678-B Polyurea acrylate oligomer and preparation method and application method thereof 浙江大学 2022-04-29 CN claimed
CN-113072678-A Polyurea acrylate oligomer and preparation method and application method thereof 浙江大学 2021-07-06 CN claimed
EP-3817826-A2 MULTICOMPONENT COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-05-12 EP disclosed
WO-2020008073-A9 MULTICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-04-23 WO disclosed
WO-2020008073-A2 MULTICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-01-09 WO disclosed
US-6042981-A Coated carrier XEROX CORPORATION (US) 2000-03-28 US disclosed