Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570748 | 0.85 | TDP1 (0.39) | APPTDP1CYP3A4ALDH1A1THRB | |
| SCHEMBL22773402 | 0.83 | MEN1 (0.46) | APPALDH1A1THRBALOX15GAA | |
| SCHEMBL28741050 | 0.80 | MAPT (0.48) | APPTDP1CYP3A4ALDH1A1THRB | |
| SCHEMBL10713204 | 0.80 | TDP1 (0.54) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL14351550 | 0.79 | ALDH1A1 (0.52) | APPTDP1CYP3A4ALDH1A1THRB | |
| SCHEMBL6572249 | 0.78 | MAPT (0.44) | TDP1CYP3A4ALDH1A1GAAMAPT | |
| SCHEMBL22517453 | 0.78 | TDP1 (0.50) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL16961438 | 0.77 | MAPT (0.50) | APPTDP1CYP3A4ALDH1A1THRB | |
| SCHEMBL3718540 | 0.76 | HPGD (0.59) | APPTDP1ALDH1A1ALOX15GAA | |
| SCHEMBL18173610 | 0.76 | HPGD (0.64) | APPTDP1CYP3A4ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080929-A | Stabilized filler compositions for cable and wire | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-06-27 | — | — | US | disclosed |