Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24690513 | 0.85 | MAPT (0.61) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL8170481 | 0.83 | APP (0.49) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL11935945 | 0.82 | MAPT (0.61) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL11935858 | 0.80 | MAPT (0.67) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL27305389 | 0.80 | MAPT (0.67) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL22783760 | 0.77 | MAPT (0.71) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL14071631 | 0.73 | FFAR1 (0.51) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL5884382 | 0.72 | ACHE (0.59) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL455536 | 0.72 | MEN1 (0.50) | MEN1MAPTKMT2AL3MBTL1KDM4E | |
| SCHEMBL5154356 | 0.72 | MEN1 (0.50) | MEN1MAPTKMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129782-B2 | Derivatives of PPD useful for coloring hair and skin | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2021-09-28 | — | — | US | claimed |
| US-20200390670-A1 | DERIVATIVES OF PPD USEFUL FOR COLORING HAIR AND SKIN | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2020-12-17 | — | — | US | claimed |
| US-11129782-B2 | Derivatives of PPD useful for coloring hair and skin | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2021-09-28 | — | — | US | disclosed |
| US-20200390670-A1 | DERIVATIVES OF PPD USEFUL FOR COLORING HAIR AND SKIN | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11129782-B2 | Derivatives of PPD useful for coloring hair and skin | TST, SDHB, NDUFS3 | MEN1 4138/4885MAPT 2765/4885KMT2A 4548/4885 |
| US-20200390670-A1 | DERIVATIVES OF PPD USEFUL FOR COLORING HAIR AND SKIN | TST, SDHB, NDUFS3 | MEN1 4138/4885MAPT 2765/4885KMT2A 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.