Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 6/20 | 0.35 |
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | CA2 | P00918 | 6/20 | 0.35 |
| ▸ | CA7 | P43166 | 6/20 | 0.35 |
| ▸ | CA9 | Q16790 | 6/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819397 | 0.81 | CHRM3 (0.35) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL818505 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EUSP2LMNAHSD17B10 | |
| SCHEMBL818063 | 0.80 | ALDH1A1 (0.41) | ALDH1A1ADORA2BMAPTTSHR | |
| SCHEMBL817065 | 0.77 | LMNA (0.38) | ALDH1A1KDM4ELMNACA12CA1 | |
| SCHEMBL818926 | 0.77 | CA12 (0.42) | ALDH1A1KDM4EUSP2LMNAHSD17B10 | |
| SCHEMBL818362 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNAHSD17B10ADORA2B | |
| SCHEMBL818848 | 0.74 | CA12 (0.44) | ALDH1A1KDM4EUSP2LMNAHSD17B10 | |
| SCHEMBL818810 | 0.73 | TSHR (0.43) | ALDH1A1LMNAHSD17B10HPGDTDP1 | |
| SCHEMBL818234 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL818675 | 0.67 | CA12 (0.40) | ALDH1A1KDM4EUSP2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |