Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818362 | 0.88 | ALDH1A1 (0.40) | LMNAKDM4ETSHRRAB9AGAA | |
| SCHEMBL819046 | 0.84 | TSHR (0.44) | LMNAKDM4ETSHRRAB9AESR1 | |
| SCHEMBL818063 | 0.83 | ALDH1A1 (0.41) | TSHRRAB9AMAPTALDH1A1POLB | |
| SCHEMBL818234 | 0.83 | ALDH1A1 (0.46) | LMNAKDM4ETSHRRAB9AESR1 | |
| SCHEMBL819397 | 0.81 | CHRM3 (0.35) | LMNAKDM4ETSHRRAB9AMAPT | |
| SCHEMBL818614 | 0.81 | LMNA (0.43) | LMNAKDM4ETSHRRAB9AGAA | |
| SCHEMBL817062 | 0.77 | ALDH1A1 (0.37) | LMNAKDM4ETSHRCA12CA1 | |
| SCHEMBL819891 | 0.77 | TSHR (0.45) | LMNAKDM4ETSHRGAACA12 | |
| SCHEMBL818456 | 0.74 | CA12 (0.44) | LMNAKDM4ETSHRRAB9AGAA | |
| SCHEMBL31196992 | 0.73 | TSHR (0.48) | LMNAKDM4ETSHRGAACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |