Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817936 | 0.93 | MAPT (0.43) | L3MBTL1MAPTSMN1; SMN2BRD4SCN8A | |
| SCHEMBL814832 | 0.79 | MAPT (0.44) | L3MBTL1MAPTHTR1ADRD2HTR2A | |
| SCHEMBL16448973 | 0.77 | BRD4 (0.53) | BRD4SCN8AHTR1ADRD2HTR2A | |
| SCHEMBL815657 | 0.76 | LMNA (0.44) | L3MBTL1MAPTSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL814826 | 0.76 | SCN8A (0.35) | L3MBTL1MAPTSMN1; SMN2SCN8AALDH1A1 | |
| SCHEMBL29864603 | 0.76 | SCN8A (0.35) | L3MBTL1MAPTSMN1; SMN2SCN8AALDH1A1 | |
| SCHEMBL18639409 | 0.73 | MAPK1 (0.47) | L3MBTL1MAPTSMN1; SMN2BRD4PTPN1 | |
| SCHEMBL282134 | 0.73 | ALDH1A1 (0.53) | PTPN1ALDH1A1HPGD | |
| SCHEMBL815456 | 0.72 | LMNA (0.48) | L3MBTL1MAPTSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL26963249 | 0.72 | SCN8A (0.35) | SCN8AALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000108-B2 | Process for selectively polymerizing ethylene and catalyst therefor | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-04-07 | — | — | US | disclosed |
| US-9000108-B2 | Process for selectively polymerizing ethylene and catalyst therefor | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-04-07 | — | — | US | disclosed |
| US-20140163186-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140163186-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-06-12 | — | — | US | disclosed |
| US-8609794-B2 | Process for selectively polymerizing ethylene and catalyst therefor | DOW GLOBAL TECHNOLOGIES, LLC. (US) | 2013-12-17 | — | — | US | disclosed |
| EP-2491062-B1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-11 | — | — | EP | disclosed |
| EP-2491062-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | Dow Global Technologies LLC (US) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011146291-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-17 | — | — | US | disclosed |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | WEE2, NOTUM, WEE1 | L3MBTL1 3645/4885MAPT 1699/4885SMN1; SMN2 4498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.