SCHEMBL814832

SCHEMBL814832

Cc1cc(C)c(OCCCOc2c(C)cc(C)cc2I)c(I)c1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
L3MBTL1 Q9Y468 4/20 0.44
LMNA P02545 2/20 0.42
KMT2A Q03164 4/20 0.41
HTR1A P08908 4/20 0.41
MEN1 O00255 3/20 0.41
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
ATM Q13315 1/20 0.36
DRD2 P14416 1/20 0.35
HTR2A P28223 1/20 0.35
HTR7 P34969 1/20 0.35
ADRA1A P35348 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15783301 0.89 MAPT (0.38) MAPTL3MBTL1LMNAKMT2AHTR1A
SCHEMBL22333152 0.88 HTR1A (0.49) MAPTL3MBTL1LMNAKMT2AHTR1A
SCHEMBL817936 0.88 MAPT (0.43) MAPTL3MBTL1LMNAKMT2AHTR1A
SCHEMBL15783299 0.82 ALDH1A1 (0.36) MAPTL3MBTL1LMNAKMT2AMEN1
SCHEMBL15783302 0.81 AR (0.33) MAPTL3MBTL1LMNAKMT2AHTR1A
SCHEMBL814826 0.80 SCN8A (0.35) MAPTL3MBTL1LMNAKMT2AMEN1
SCHEMBL29864603 0.80 SCN8A (0.35) MAPTL3MBTL1LMNAKMT2AMEN1
SCHEMBL815657 0.80 LMNA (0.44) MAPTL3MBTL1LMNAKMT2AMEN1
SCHEMBL26964167 0.79 PTGS2 (0.42) LMNAKMT2AMEN1ALDH1A1MAPK1
SCHEMBL817113 0.79 L3MBTL1 (0.38) MAPTL3MBTL1LMNAHTR1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9000108-B2 Process for selectively polymerizing ethylene and catalyst therefor DOW GLOBAL TECHNOLOGIES LLC (US) 2015-04-07 US disclosed
US-9000108-B2 Process for selectively polymerizing ethylene and catalyst therefor DOW GLOBAL TECHNOLOGIES LLC (US) 2015-04-07 US disclosed
US-20140163186-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2014-06-12 US disclosed
US-20140163186-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2014-06-12 US disclosed
US-8609794-B2 Process for selectively polymerizing ethylene and catalyst therefor DOW GLOBAL TECHNOLOGIES, LLC. (US) 2013-12-17 US disclosed
EP-2491062-B1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-12-11 EP disclosed
EP-2491062-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR Dow Global Technologies LLC (US) 2012-08-29 EP disclosed
WO-2011146291-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO disclosed
WO-2011146044-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO disclosed
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC 2011-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR WEE2, NOTUM, WEE1 MAPT 1699/4885L3MBTL1 3645/4885LMNA 1982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.