Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171863 | 1.00 | PIM1 (0.46) | PIM1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8310560 | 0.86 | PIM1 (0.64) | PIM1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8310559 | 0.86 | PIM1 (0.64) | PIM1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8173766 | 0.77 | PIM1 (0.74) | PIM1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8173768 | 0.77 | PIM1 (0.74) | PIM1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL1250373 | 0.75 | CISD1 (0.64) | PIM1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1250371 | 0.75 | CISD1 (0.64) | PIM1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8173296 | 0.71 | PIM1 (0.51) | PIM1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8173297 | 0.71 | PIM1 (0.51) | PIM1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL3090738 | 0.68 | MAPT (0.56) | MEN1MAPTKMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |