Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684400 | 0.89 | CASP1 (0.39) | ALDH1A1MEN1KMT2ACASP1TRPV1 | |
| SCHEMBL8172773 | 0.86 | ALDH1A1 (0.40) | ALDH1A1NPSR1RAB9ANPC1MAPT | |
| SCHEMBL7684425 | 0.85 | CASP1 (0.38) | ALDH1A1MEN1KMT2ACASP1 | |
| SCHEMBL8172706 | 0.84 | MAPT (0.44) | ALDH1A1MAPTTHRBSMN1; SMN2MEN1 | |
| SCHEMBL8176695 | 0.83 | CASP1 (0.44) | ALDH1A1MAPTTHRBSMN1; SMN2CASP1 | |
| SCHEMBL8177154 | 0.82 | MAPK1 (0.39) | ALDH1A1NPSR1RAB9AMAPTTHRB | |
| SCHEMBL7684215 | 0.81 | CASP1 (0.40) | ALDH1A1TSHRCASP1TRPV1P2RX7 | |
| SCHEMBL7680016 | 0.79 | CASP1 (0.48) | CASP1 | |
| SCHEMBL7686569 | 0.78 | CASP1 (0.47) | RAB9ANPC1SMN1; SMN2CASP1 | |
| Hydrochloric Acid SCHEMBL7689843 | 0.78 | MAPK1 (0.39) | ALDH1A1NPSR1MAPTTHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |