Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095868 | 1.00 | HTR1A (0.57) | HTR1APLAUPRCPPNMT | |
| SCHEMBL4107088 | 0.88 | HTR1A (0.46) | HTR1APLAUPRCP | |
| SCHEMBL4107087 | 0.88 | HTR1A (0.46) | HTR1APLAUPRCP | |
| SCHEMBL10763815 | 0.88 | HTR1A (0.46) | HTR1APLAUPRCP | |
| SCHEMBL4107085 | 0.88 | HTR1A (0.46) | HTR1APLAUPRCP | |
| Bromide SCHEMBL11766425 | 0.86 | HTR1A (0.45) | HTR1APLAUPRCP | |
| Bromide SCHEMBL11766417 | 0.86 | HTR1A (0.45) | HTR1APLAUPRCP | |
| SCHEMBL20833280 | 0.78 | MBTD1 (0.42) | HTR1APRCP | |
| SCHEMBL26725468 | 0.78 | MBTD1 (0.42) | HTR1APRCP | |
| SCHEMBL11230349 | 0.77 | HTR1A (0.48) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080752-A | FOR TREATING CONDITION WHICH REQUIRES ANTAGONISM OF A DOPAMINE RECEPTOR SUCH AS PSYCHTIC CONDITION | SMITHKLINE BEECHAM PLC (GB) | 2000-06-27 | — | — | US | disclosed |