SCHEMBL817283

SCHEMBL817283

Cc1ccccc1SOSc1ccccc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.45
TSHR P16473 2/20 0.45
HAO1 Q9UJM8 1/20 0.38
MCHR1 Q99705 1/20 0.36
ALDH1A1 P00352 3/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
ESR1 P03372 1/20 0.36
HTR1A P08908 2/20 0.35
HTR3A P46098 2/20 0.35
CYP3A4 P08684 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
AR P10275 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP2A6 P11509 2/20 0.33
RAB9A P51151 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1688313 0.82 TSHR (0.43) ACHETSHRHAO1MCHR1ALDH1A1
SCHEMBL12052507 0.77 TSHR (0.38) ACHETSHRHAO1MCHR1ALDH1A1
SCHEMBL8148762 0.77 ACHE (0.38) ACHETSHRHAO1MCHR1ALDH1A1
SCHEMBL22683247 0.76
SCHEMBL29468536 0.75 ACHE (0.53) ACHETSHRHAO1MCHR1ALDH1A1
SCHEMBL576094 0.75 ACHE (0.53) ACHETSHRHAO1MCHR1ALDH1A1
SCHEMBL57312 0.75 ACHE (0.53) ACHETSHRHAO1MCHR1ALDH1A1
SCHEMBL29411690 0.75 ACHE (0.53) ACHETSHRHAO1MCHR1ALDH1A1
Hydrogen Sulfide SCHEMBL11580912 0.72 HTR1A (0.50) ACHETSHRHAO1MCHR1ALDH1A1
SCHEMBL4231323 0.72 ACHE (0.50) ACHETSHRHAO1MCHR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192492-B1 PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1992-01-02 EP claimed
CN-119371342-A Method for selective photocatalytic oxidation of thioether compounds into sulfone compounds 遵义医科大学 2025-01-28 CN disclosed
CN-113527697-B Waugh type polyoxometallate base metal-organic complex for efficient catalytic oxidation desulfurization and application thereof 渤海大学 2022-10-14 CN disclosed
CN-114057838-B Solid-phase synthesis method of acetyl hexapeptide-8 浙江湃肽生物有限公司南京分公司 2022-04-12 CN disclosed
CN-114057838-A Solid-phase synthesis method of acetyl hexapeptide-8 浙江湃肽生物有限公司南京分公司 2022-02-18 CN disclosed
CN-113527697-A Waugh type polyoxometallate base metal-organic complex for efficient catalytic oxidation desulfurization and application thereof 渤海大学 2021-10-22 CN disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
CN-104220466-B For the method preparing polydiene 株式会社普利司通 2016-09-21 CN disclosed
EP-2465819-B1 METHOD FOR PURIFYING CHLOROSILANES SHINETSU CHEMICAL CO (JP) 2016-06-29 EP disclosed
CN-103259044-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEMICAL CORP. (JP) 2016-02-10 CN disclosed
CN-1367800-A Process for producing ethylene/olefin interpolymers EASTMAN CHEM CO (US) 2002-09-04 CN disclosed
US-4677193-A GONADOTROPIN-RELEASING FACTOR ANALOGS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1987-06-30 US disclosed
EP-0192492-A2 Peptides containing an aliphatic-aromatic ketone side chain THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1986-08-27 EP disclosed
EP-0067416-B1 CATALYTIC COMPONENT FOR POLYMERIZATION OF ALPHA-OLEFIN AND METHOD FOR HOMO- OR CO-POLYMERIZATION OF ALPHA-OLEFIN TOYO STAUFFER CHEMICAL CO. LTD. (JP) 1986-05-07 EP disclosed
US-4525558-A COORDINATION POLYMERIZATION CATALYST CONTAINING ORGANOMAGNESIUM COMPOUND, CARBON TETRACHLORIDE, ELECTRON DONOR, PHENOL AND HALOGENATED TITANIUM COMPOUND TOYO STAUFFER CHEMICAL CO., LTD. (JP) 1985-06-25 US disclosed
US-4439539-A Catalytic component for polymerization of α-olefin and method for homo- or co-polymerization of α-olefin TOYO STAUFFER CHEMICAL CO., LTD. (JP) 1984-03-27 US disclosed
US-4439541-A Catalytic component for polymerization of α-olefin and method for homo- or co-polymerization of α-olefin TOYO STAUFFER CHEMICAL CO., LTD. (JP) 1984-03-27 US disclosed
EP-0067417-A2 Catalytic component for polymerization of alpha-olefin and method for homo-or co-polymerization of alpha-olefin TOYO STAUFFER CHEMICAL CO. LTD. (JP) 1982-12-22 EP disclosed
EP-0067416-A2 Catalytic component for polymerization of alpha-olefin and method for homo- or co-polymerization of alpha-olefin TOYO STAUFFER CHEMICAL CO. LTD. (JP) 1982-12-22 EP disclosed
US-4187385-A TITANIUM COMPONENT COPULVERIZED WITH ORGANOALUMINUM COMPOUND AND ETHYLENE OR A-OLEFINS, PARTICLE SIZE MITSUI TOATSU CHEMICAL, INC. (JP) 1980-02-05 US disclosed