Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818486 | 0.83 | TSHR (0.40) | ALDH1A1TSHRMAPTSMN1; SMN2TDP1 | |
| SCHEMBL817764 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPTSMN1; SMN2ADORA2B | |
| SCHEMBL818164 | 0.77 | TSHR (0.45) | ALDH1A1TSHRSMN1; SMN2TDP1 | |
| SCHEMBL817432 | 0.76 | TDP1 (0.35) | TSHRMAPTPOLBTDP1KDM4E | |
| SCHEMBL819124 | 0.76 | TSHR (0.46) | ALDH1A1TSHRMAPTPOLBNPC1 | |
| SCHEMBL819445 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTCACNA1FCACNA1D | |
| SCHEMBL817707 | 0.75 | TSHR (0.50) | ALDH1A1TSHRMAPTCACNA1FCACNA1D | |
| SCHEMBL818586 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPTPOLBNPC1 | |
| SCHEMBL818240 | 0.72 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTCACNA1FCACNA1D | |
| SCHEMBL818206 | 0.72 | TSHR (0.47) | ALDH1A1TSHRMAPTCACNA1FCACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |