Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA7 | P43166 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31196992 | 0.89 | TSHR (0.48) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL817764 | 0.88 | ALDH1A1 (0.42) | TSHRMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL818164 | 0.85 | TSHR (0.45) | TSHRALDH1A1SMN1; SMN2HPGDESR1 | |
| SCHEMBL819124 | 0.84 | TSHR (0.46) | TSHRMAPTALDH1A1ESR1CYP3A4 | |
| SCHEMBL817302 | 0.83 | ALDH1A1 (0.44) | TSHRMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL818586 | 0.83 | ALDH1A1 (0.48) | TSHRMAPTALDH1A1ESR1CYP3A4 | |
| SCHEMBL817432 | 0.81 | TDP1 (0.35) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL818563 | 0.78 | ALDH1A1 (0.53) | TSHRCA2ALDH1A1CYP3A4LMNA | |
| SCHEMBL819133 | 0.74 | TSHR (0.39) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL819891 | 0.73 | TSHR (0.45) | TSHRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |