Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173133 | 0.86 | CTSS (0.38) | — | |
| SCHEMBL4670471 | 0.79 | ADRB2 (0.39) | DHODHMAPTADRB2ADRB1ADRB3 | |
| SCHEMBL4677838 | 0.78 | NFE2L2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4670041 | 0.78 | ADRB2 (0.42) | DHODHADRB2ADRB1ADRB3 | |
| SCHEMBL4670482 | 0.77 | DHODH (0.36) | DHODH | |
| Water SCHEMBL4673070 | 0.77 | ADRB2 (0.42) | DHODHMAPTADRB2ADRB1ADRB3 | |
| SCHEMBL4670626 | 0.77 | ADRB2 (0.40) | MAPTADRB2ADRB1ADRB3 | |
| Water SCHEMBL4672111 | 0.77 | ADRB2 (0.42) | DHODHMAPTADRB2ADRB1ADRB3 | |
| SCHEMBL4670059 | 0.77 | ADRB2 (0.42) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4670426 | 0.76 | ADRB2 (0.38) | DHODHMAPTADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051586-A | HYPOGLYCEMIC AGENTS; ANTIDIABETIC AGENTS | BAYER CORPORATION (US) | 2000-04-18 | — | — | US | disclosed |