Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.48 |
| ▸ | ICMT | O60725 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13931408 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAPPARGPPARDPPARA | |
| SCHEMBL8188581 | 0.91 | ALDH1A1 (0.62) | ALDH1A1LMNAPPARGPPARDPPARA | |
| SCHEMBL13931407 | 0.90 | ALDH1A1 (0.60) | ALDH1A1LMNAPPARGPPARDPPARA | |
| SCHEMBL8173991 | 0.88 | ALDH1A1 (0.58) | ALDH1A1LMNAPPARGPPARDPPARA | |
| SCHEMBL13931405 | 0.87 | ALDH1A1 (0.59) | ALDH1A1LMNAPPARGPPARDPPARA | |
| SCHEMBL8171623 | 0.85 | ALDH1A1 (0.64) | ALDH1A1LMNAPPARGPPARDPPARA | |
| SCHEMBL8165182 | 0.84 | ALDH1A1 (0.63) | ALDH1A1LMNAPPARGPPARDPPARA | |
| SCHEMBL13931023 | 0.84 | LMNA (0.71) | ALDH1A1LMNAPPARGPPARDPPARA | |
| SCHEMBL8174542 | 0.83 | LMNA (0.70) | ALDH1A1LMNAPPARGPPARDPPARA | |
| SCHEMBL8167192 | 0.83 | PLA2G2A (0.60) | ALDH1A1LMNAPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100867-A2 | NOVEL INHIBITORS HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2008-08-21 | — | — | WO | disclosed |