Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176766 | 0.87 | ALDH1A1 (0.50) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8184284 | 0.86 | ALDH1A1 (0.49) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL8189042 | 0.86 | MEN1 (0.53) | KMT2AMEN1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL7109075 | 0.86 | MAPT (0.50) | KMT2AMEN1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL8183724 | 0.85 | MAPT (0.47) | KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8184203 | 0.85 | KMT2A (0.42) | KMT2AMEN1ABCB1ABCG2MAPK1 | |
| SCHEMBL8184226 | 0.85 | KMT2A (0.46) | KMT2AMEN1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL7799989 | 0.85 | ALDH1A1 (0.44) | KMT2AMEN1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL8175630 | 0.84 | RAB9A (0.56) | KMT2AMEN1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL8185113 | 0.84 | MAPK1 (0.47) | KMT2AMEN1IRAK4MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110934-A | Substituted benzamide derivatives and their use as anticonvulsants | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-08-29 | — | — | US | disclosed |
| EP-0906283-A1 | SUBSTITUTED BENZAMIDE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997048683-A1 | SUBSTITUTED BENZAMIDE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 1997-12-24 | — | — | WO | disclosed |