Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | CRHR1 | P34998 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8163320 | 0.87 | HSD11B1 (0.45) | HSD11B1CRHR1NOTUM | |
| SCHEMBL8168903 | 0.79 | PTGS1 (0.38) | ALDH1A1NOTUM | |
| SCHEMBL8172661 | 0.79 | NOTUM (0.35) | NOTUM | |
| SCHEMBL8169618 | 0.77 | NOTUM (0.34) | NOTUM | |
| SCHEMBL12859389 | 0.77 | HSD11B1 (0.45) | HSD11B1CRHR1 | |
| SCHEMBL8569766 | 0.75 | HSD11B1 (0.47) | HSD11B1NOTUM | |
| SCHEMBL7894519 | 0.74 | NOTUM (0.32) | HSD11B1NOTUM | |
| SCHEMBL8172631 | 0.74 | ALDH1A1 (0.35) | HSD11B1ALDH1A1NOTUM | |
| SCHEMBL7778111 | 0.72 | PTGS2 (0.47) | — | |
| SCHEMBL8169536 | 0.72 | NOTUM (0.34) | ALDH1A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6054412-A | AGRICULTURE, HORTICULTURE | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-25 | — | — | US | disclosed |