Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL884541 | 0.88 | CYP2C19 (0.36) | ALDH1A1LMNAHTTSMN1; SMN2ITGB3 | |
| SCHEMBL884696 | 0.88 | POLB (0.34) | HTR7ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL884440 | 0.87 | HTR7 (0.36) | HTR7ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL884791 | 0.87 | HTR7 (0.36) | HTR7ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL885714 | 0.83 | POLB (0.35) | ALDH1A1LMNAHTTSMN1; SMN2ITGB3 | |
| SCHEMBL884320 | 0.83 | LMNA (0.39) | ALDH1A1LMNAHTTSMN1; SMN2ITGB3 | |
| SCHEMBL885599 | 0.83 | HDAC1 (0.33) | ALDH1A1LMNAHTTSMN1; SMN2ITGB3 | |
| SCHEMBL2063305 | 0.82 | MEN1 (0.34) | HTR7ALDH1A1LMNAPKMRAB9A | |
| SCHEMBL884589 | 0.82 | ALOX15 (0.36) | HTR7ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL884509 | 0.80 | HTR7 (0.37) | HTR7ALDH1A1LMNASMN1; SMN2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089005-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-07-24 | — | — | WO | disclosed |