Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 4/20 | 0.33 |
| ▸ | XIAP | P98170 | 3/20 | 0.32 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817544 | 0.87 | CTSK (0.35) | CAPN1TACR1PREPCTSKCTSS | |
| SCHEMBL820313 | 0.87 | CTSK (0.35) | CAPN1TACR1PREPCTSKCTSS | |
| SCHEMBL818270 | 0.78 | DPP8 (0.37) | — | |
| SCHEMBL2439989 | 0.69 | CTSL (0.42) | PREPXIAPBIRC3CTSLBIRC2 | |
| SCHEMBL2440300 | 0.67 | XIAP (0.32) | TNFXIAPBIRC3CTSKCTSS | |
| SCHEMBL12329404 | 0.65 | XIAP (0.49) | XIAPBIRC3BIRC2 | |
| SCHEMBL2440819 | 0.65 | XIAP (0.49) | XIAPBIRC3BIRC2 | |
| SCHEMBL12405710 | 0.64 | CTSK (0.39) | PREPXIAPBIRC3CTSKCTSS | |
| SCHEMBL2113431 | 0.64 | CTSL (0.40) | XIAPBIRC3CTSLREN | |
| SCHEMBL13449171 | 0.63 | SIGMAR1 (0.47) | PREPXIAPBIRC3BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288116-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUITCAL CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288116-A1 | IAP INHIBITORS | XIAP, BIRC5, BIRC7 | CAPN1 583/4885F2 4456/4885TACR1 4669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.