Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571512 | 0.90 | XDH (0.48) | GRM5ALDH1A1XDHHPGDMAP4K4 | |
| SCHEMBL1398503 | 0.85 | GRM5 (0.55) | GRM5ALDH1A1XDH | |
| SCHEMBL25598322 | 0.84 | GRM5 (0.52) | GRM5XDHKDM4E | |
| SCHEMBL28343052 | 0.83 | ALDH1A1 (0.50) | GRM5ALDH1A1XDHHPGDKDM4E | |
| SCHEMBL30568881 | 0.82 | KDM1A (0.60) | ALDH1A1SMN1; SMN2MAP4K4 | |
| SCHEMBL20512752 | 0.82 | KDM1A (0.60) | ALDH1A1SMN1; SMN2MAP4K4 | |
| SCHEMBL22861578 | 0.81 | XDH (0.55) | GRM5XDH | |
| SCHEMBL1495528 | 0.81 | GRM2 (0.45) | GRM5ALDH1A1SMN1; SMN2XDH | |
| SCHEMBL28577779 | 0.81 | EGFR (0.49) | GRM5XDHKDM4E | |
| SCHEMBL29788229 | 0.79 | XDH (0.60) | ALDH1A1XDHHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073789-A1 | AMPA RECEPTOR POTENTIATORS | ELI LILLY AND COMPANY (US) | 2008-06-19 | — | — | WO | disclosed |