Fluoride Ion

Fluoride Ion

SCHEMBL817671

CCC(=O)N(Cc1ccccc1)[Nd+]N(Cc1ccccc1)C(=O)CC.[F-]

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
LMNA P02545 2/20 0.47
ALDH1A1 P00352 2/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
OPRM1 P35372 2/20 0.43
TSPO P30536 2/20 0.43
POLB P06746 1/20 0.43
HSD17B10 Q99714 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
RIPK1 Q13546 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL817740 0.96 NPC1 (0.49) NPC1RAB9ALMNAALDH1A1KMT2A
Iodide SCHEMBL817230 0.96 NPC1 (0.49) NPC1RAB9ALMNAALDH1A1KMT2A
Hydrochloric Acid SCHEMBL817990 0.96 NPC1 (0.49) NPC1RAB9ALMNAALDH1A1KMT2A
Fluoride Ion SCHEMBL817566 0.86 NPC1 (0.50) NPC1RAB9ALMNAALDH1A1KMT2A
Iodide SCHEMBL817556 0.83 NPC1 (0.50) NPC1RAB9ALMNAALDH1A1KMT2A
Bromide SCHEMBL817582 0.83 NPC1 (0.50) NPC1RAB9ALMNAALDH1A1KMT2A
Hydrochloric Acid SCHEMBL816946 0.83 NPC1 (0.50) NPC1RAB9ALMNAALDH1A1KMT2A
SCHEMBL6433208 0.77 ALDH1A1 (0.64) NPC1RAB9ALMNAALDH1A1KMT2A
SCHEMBL3163935 0.76 NPC1 (0.75) NPC1RAB9AALDH1A1KMT2AMEN1
SCHEMBL17796003 0.76 ALOX5 (0.61) NPC1RAB9ALMNAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153545-B2 Process for homo—or copolymerization of conjugated olefins STYRON EUROPE GMBH (CH) 2012-04-10 US disclosed
US-20110160041-A1 PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS STYRON EUROPE GMBH 2011-06-30 US disclosed
US-7915194-B2 Process for homo- or copolymerization of conjugated olefins STYRON EUROPE GMBH (CH) 2011-03-29 US disclosed
EP-2267046-A1 Process for homo- or copolymerization of conjugated olefines DOW GLOBAL TECHNOLOGIES INC. (US) 2010-12-29 EP disclosed
US-20100248947-A1 PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-09-30 US disclosed
US-7612009-B2 Process for homo-or copolymerization of conjugated olefines DOW GLOBAL TECHNOLOGIES, INC. (US) 2009-11-03 US disclosed
US-20060142145-A1 Process for homo-or copolymerization of conjugated olefines TRINSEO EUROPE GMBH (CH) 2006-06-29 US disclosed
EP-1597292-A2 PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED OLEFINES DOW GLOBAL TECHNOLOGIES INC. (US) 2005-11-23 EP disclosed
WO-2004076504-A2 PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED OLEFINES DOW GLOBAL TECHNOLOGIES, INC. (US) 2004-09-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110160041-A1 PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS F12, ETFB, F2 NPC1 3338/4885RAB9A 4044/4885LMNA 2383/4885
US-20060142145-A1 Process for homo-or copolymerization of conjugated olefines ETFB, F12, F2 NPC1 3771/4885RAB9A 2984/4885LMNA 2248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.