Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | GPR6 | P46095 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178069 | 0.87 | MAPK14 (0.52) | MAPK14HTTCES2CES1 | |
| SCHEMBL8174865 | 0.84 | CFTR (0.46) | SCN8ASCN10AKDM4ECFTRCES2 | |
| SCHEMBL8168273 | 0.81 | CACNA1B (0.43) | SCN8ASCN10ACFTR | |
| SCHEMBL8182159 | 0.80 | TMPRSS4 (0.49) | MAPK14KDM4EHTTRXFP1CES2 | |
| SCHEMBL8175439 | 0.80 | RORB (0.46) | SCN8ASCN10AKDM4ERXFP1CES2 | |
| SCHEMBL8182920 | 0.80 | MAPK14 (0.56) | MAPK14HTTCES2CES1GAA | |
| SCHEMBL8182789 | 0.79 | MAPK14 (0.41) | SCN8ASCN10AMAPK14KDM4EHTT | |
| SCHEMBL8168954 | 0.78 | MAPK14 (0.46) | MAPK14HTTCES2CES1 | |
| SCHEMBL8168938 | 0.77 | TRIM24 (0.42) | KDM4ECFTR | |
| SCHEMBL28188798 | 0.77 | GAA (0.57) | KDM4EHTTRXFP1CFTRCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063176-A2 | DISUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES AND FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-26 | — | — | WO | disclosed |