Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176045 | 0.85 | CES2 (0.40) | CES2CES1GPBAR1SCN8ASCN10A | |
| SCHEMBL8168125 | 0.81 | CES2 (0.40) | CES2CES1GPBAR1SCN8ASCN10A | |
| SCHEMBL8177263 | 0.79 | SCN8A (0.46) | MAPK14CES2CES1SCN8ASCN10A | |
| SCHEMBL8168954 | 0.76 | MAPK14 (0.46) | MAPK14CES2CES1HTTKMT2A | |
| SCHEMBL22114934 | 0.76 | HSD17B10 (0.44) | CES2KDM4ETMPRSS4 | |
| SCHEMBL8176775 | 0.75 | CES2 (0.47) | MAPK14CES2CES1HTTKMT2A | |
| SCHEMBL12247362 | 0.75 | CES2 (0.41) | CES2HTTKMT2ATMPRSS4 | |
| SCHEMBL30343770 | 0.75 | NOTUM (0.50) | CES2KDM4ETMPRSS4 | |
| SCHEMBL8175847 | 0.74 | SMO (0.43) | RXFP1KMT2ATMPRSS4 | |
| SCHEMBL8182159 | 0.72 | TMPRSS4 (0.49) | MAPK14CES2CES1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063176-A2 | DISUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES AND FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-26 | — | — | WO | disclosed |