Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.60 |
| ▸ | ITGAV | P06756 | 17/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.54 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177163 | 0.91 | ITGB3 (0.51) | ITGB3ITGAVITGA2BMALT1 | |
| SCHEMBL8177114 | 0.84 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL8177121 | 0.84 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL7371595 | 0.82 | ITGB3 (0.51) | ITGB3ITGAVITGA2B | |
| SCHEMBL7371601 | 0.82 | ITGB3 (0.51) | ITGB3ITGAVITGA2B | |
| SCHEMBL8177321 | 0.80 | ITGB3 (0.42) | ITGB3ITGAVITGA2B | |
| SCHEMBL7373310 | 0.79 | ITGB3 (0.43) | ITGB3ITGAVITGA2BMALT1 | |
| SCHEMBL7374249 | 0.79 | ITGB3 (0.43) | ITGB3ITGAVITGA2BMALT1 | |
| SCHEMBL8168332 | 0.78 | ITGB3 (0.56) | ITGB3ITGAVITGA2B | |
| SCHEMBL13059982 | 0.78 | ITGB3 (0.63) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153628-A | 1,3,4-thiadiazoles and 1,3,4-Oxadiazoles as αv β3 antagonists | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-28 | — | — | US | disclosed |