Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.61 |
| ▸ | ITGAV | P06756 | 13/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177121 | 1.00 | ITGB3 (0.61) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL7371601 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BITGAVGLS | |
| SCHEMBL7371595 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BITGAVGLS | |
| SCHEMBL8177327 | 0.84 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL7368311 | 0.83 | ANPEP (0.45) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL8177321 | 0.79 | ITGB3 (0.42) | ITGB3ITGA2BITGAVGLS | |
| SCHEMBL7368318 | 0.78 | GLS (0.42) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL7368315 | 0.78 | GLS (0.42) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL8168274 | 0.77 | ITGB3 (0.63) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL8179651 | 0.77 | ITGAV (0.63) | ITGB3ITGA2BITGAVITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153628-A | 1,3,4-thiadiazoles and 1,3,4-Oxadiazoles as αv β3 antagonists | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-28 | — | — | US | claimed |
| US-6153628-A | 1,3,4-thiadiazoles and 1,3,4-Oxadiazoles as αv β3 antagonists | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-28 | — | — | US | disclosed |