Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291983 | 0.82 | L3MBTL1 (0.41) | L3MBTL1SMN1; SMN2LMNATSHRKDM4E | |
| SCHEMBL13891403 | 0.82 | BCHE (0.51) | L3MBTL1SMN1; SMN2BCHENPC1RAB9A | |
| SCHEMBL18130834 | 0.78 | KDM2B (0.50) | LMNATSHRCYP2C19 | |
| SCHEMBL13956309 | 0.77 | SMN1; SMN2 (0.39) | L3MBTL1SMN1; SMN2LMNAKDM4EBCHE | |
| SCHEMBL19514340 | 0.76 | LTA4H (0.47) | L3MBTL1SMN1; SMN2LMNATSHRKDM4E | |
| SCHEMBL16050255 | 0.76 | SMN1; SMN2 (0.42) | L3MBTL1SMN1; SMN2LMNAKDM4EBCHE | |
| SCHEMBL14456689 | 0.75 | MAPT (0.56) | SMN1; SMN2LMNAKDM4E | |
| SCHEMBL11174725 | 0.74 | KDM4E (0.36) | L3MBTL1SMN1; SMN2LMNATSHRKDM4E | |
| SCHEMBL1052748 | 0.74 | HRH3 (0.47) | SMN1; SMN2TSHR | |
| SCHEMBL3897207 | 0.74 | GPR119 (0.50) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084610-B2 | Compositions and methods for detecting and treating tumors containing acidic areas | SUMMERTON JAMES EDWARD (US) | 2011-12-27 | — | — | US | disclosed |
| US-20080124274-A1 | Compositions and methods for detecting and treating tumors containing acidic areas | SUMMERTON JAMES EDWARD | 2008-05-29 | — | — | US | disclosed |
| US-20070286803-A1 | Compositions and methods for detecting and treating tumors containing acidic areas | SUMMERTON JAMES EDWARD | 2007-12-13 | — | — | US | disclosed |
| US-20070231256-A1 | Compositions and methods for detecting and treating tumors containing acidic areas | SUMMERTON JAMES E | 2007-10-04 | — | — | US | disclosed |
| US-6090825-A | Oxazole derivatives as antagonists of alpha 1C andrenergic receptors | GLAXO WELLCOME INC. (US) | 2000-07-18 | — | — | US | disclosed |
| EP-0793658-A1 | OXAZOLE DERIVATIVES AS ANTAGONISTS OF ALPHA-1C ADRENERGIC RECEPTORS | GLAXO WELLCOME INC. (US) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016049-A1 | OXAZOLE DERIVATIVES AS ANTAGONISTS OF α-1C ADRENERGIC RECEPTORS | GLAXO WELLCOME INC. (US) | 1996-05-30 | — | — | WO | disclosed |