Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 11/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551129 | 1.00 | TACR1 (0.38) | TACR1MAOAMAOBALDH1A1CRHBP | |
| SCHEMBL8171940 | 0.84 | CASR (0.39) | TACR1MAOBHTT | |
| SCHEMBL4088596 | 0.84 | CASR (0.39) | TACR1MAOBHTT | |
| SCHEMBL3975545 | 0.83 | HTT (0.44) | TSHRHTT | |
| SCHEMBL4746758 | 0.83 | HTT (0.44) | TSHRHTT | |
| SCHEMBL13885375 | 0.82 | TACR1 (0.34) | TACR1MAOAMAOBALDH1A1CRHBP | |
| SCHEMBL4743482 | 0.81 | TACR1 (0.34) | TACR1MAOBPREP | |
| SCHEMBL8172060 | 0.78 | REN (0.34) | ALDH1A1TSHRHTT | |
| SCHEMBL13885022 | 0.77 | TDP1 (0.38) | ALDH1A1HTT | |
| SCHEMBL3985082 | 0.77 | HTR1A (0.33) | ALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053277-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2009-04-30 | — | — | WO | disclosed |
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |