Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | TST | Q16762 | 1/20 | 0.50 |
| ▸ | VDR | P11473 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8180236 | 0.90 | VDR (0.49) | LMNAADRA1AALDH1A1ALOX15CYP3A4 | |
| SCHEMBL8189784 | 0.90 | VDR (0.49) | LMNAADRA1AALDH1A1ALOX15CYP3A4 | |
| SCHEMBL7718670 | 0.89 | LMNA (0.51) | LMNAADRA1AALDH1A1ALOX15CYP3A4 | |
| SCHEMBL8193552 | 0.88 | ALDH1A1 (0.48) | LMNAADRA1AALDH1A1ALOX15CYP3A4 | |
| SCHEMBL7714416 | 0.85 | ALDH1A1 (0.51) | LMNAADRA1AALDH1A1ALOX15CYP3A4 | |
| SCHEMBL5433038 | 0.84 | VDR (0.60) | LMNAADRA1AALDH1A1ALOX15CYP3A4 | |
| SCHEMBL6045249 | 0.84 | VDR (0.60) | LMNAADRA1AALDH1A1ALOX15CYP3A4 | |
| SCHEMBL5438456 | 0.84 | VDR (0.60) | LMNAADRA1AALDH1A1ALOX15CYP3A4 | |
| SCHEMBL8529627 | 0.84 | VDR (0.52) | LMNAADRA1AALDH1A1ALOX15CYP3A4 | |
| SCHEMBL9265818 | 0.84 | VDR (0.52) | LMNAADRA1AALDH1A1ALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832063-B1 | VITAMIN D DERIVATIVES WITH C-25 SUBSTITUENTS, PROCESS FOR THEIR PREPARATION, INTERMEDIATE PRODUCTS AND THEIR USE IN PREPARING MEDICAMENTS | SCHERING AG (DE) | 2000-02-23 | — | — | EP | disclosed |