SCHEMBL817965

SCHEMBL817965

CC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Hf](Cl)(Cl)(C1C(C(C)C)=Cc2c(-c3cccc4ccccc34)cccc21)[SiH](C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27478572 0.94 NPC1 (0.36) NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL5890213 0.93 NPC1 (0.35) NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL818878 0.91 KDM4E (0.34) NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL818446 0.90
SCHEMBL1120691 0.86
SCHEMBL5889869 0.83
SCHEMBL5890665 0.83 NPC1 (0.33) NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL5890334 0.81
Hydrochloric Acid SCHEMBL817966 0.81
SCHEMBL8604997 0.80 KDM4E (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2673315-B1 POLYETHYLENE FILMS EQUISTAR CHEM LP (US) 2019-03-20 EP disclosed
EP-1943281-B1 HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE BASELL POLYOLEFINE GMBH (DE) 2017-09-20 EP disclosed
US-9676971-B2 Systems, methods and compositions for production of tie-layer adhesives EQUISTAR CHEMICALS, LP (US) 2017-06-13 US disclosed
US-20160222257-A1 SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES EQUISTAR CHEMICALS, LP (US) 2016-08-04 US disclosed
US-9321945-B2 Systems, methods and compositions for production of tie-layer adhesives EQUISTAR CHEMICALS, LP (US) 2016-04-26 US disclosed
US-9029478-B2 High clarity polyethylene films EQUISTAR CHEMICALS, LP (US) 2015-05-12 US disclosed
EP-2114567-B1 IRON COMPLEXES AND THEIR USE IN POLYMERIZATION PROCESSES BASELL POLYOLEFINE GMBH (DE) 2015-04-15 EP disclosed
US-8865834-B2 Adhesive polymer composition BASELL POLYOLEFINE GMBH (DE) 2014-10-21 US disclosed
EP-2760958-A1 SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES Equistar Chemicals, LP (US) 2014-08-06 EP disclosed
US-8722833-B2 Multimodal polyethylene composition, mixed catalyst and process for preparing the composition BASELL POLYOLEFINE GMBH (DE) 2014-05-13 US disclosed
EP-1753794-B8 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION BASELL POLYOLEFINE GMBH (DE) 2008-07-16 EP disclosed
WO-2008077530-A2 MULTIMODAL POLYETHYLENE COMPOSITION, MIXED CATALYST AND PROCESS FOR PREPARING THE COMPOSITION BASELL POLYOLEFINE GMBH (DE) 2008-07-03 WO disclosed
EP-1753794-B1 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION BASELL POLYOLEFINE GMBH (DE) 2008-06-04 EP disclosed
US-20070255033-A1 Polyethylene for Injection Moldings BASELL POYOLEFINE GMBH (DE) 2007-11-01 US disclosed
US-20070213205-A1 Polyethylene and Catalyst Composition for its Preparation BASELL POLYOLEFINE GMBH (DE) 2007-09-13 US disclosed
WO-2007042252-A1 HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE BASELL POLYOLEFINE GMBH (DE) 2007-04-19 WO disclosed
EP-1753794-A1 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION Basell Polyolefine GmbH (DE) 2007-02-21 EP disclosed
EP-1740623-A1 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION Basell Polyolefine GmbH (DE) 2007-01-10 EP disclosed
WO-2005103100-A1 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION BASELL POLYOLEFINE GMBH (DE) 2005-11-03 WO disclosed
WO-2005103095-A1 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION BASELL POLYOLEFINE GMBH (DE) 2005-11-03 WO disclosed