SCHEMBL818446

SCHEMBL818446

CC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Hf](Cl)(Cl)(C1C(C(C)C)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21)[SiH](C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1120733 0.92
SCHEMBL817965 0.90 NPC1 (0.33)
SCHEMBL1120750 0.88
SCHEMBL817431 0.87
SCHEMBL27478572 0.85 NPC1 (0.36)
SCHEMBL5890213 0.84 NPC1 (0.35)
SCHEMBL818247 0.84 NR1H4 (0.31)
SCHEMBL1120691 0.83
SCHEMBL818878 0.82 KDM4E (0.34)
SCHEMBL9937426 0.80 GPR84 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2760958-B1 SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES EQUISTAR CHEM LP (US) 2020-08-12 EP disclosed
EP-2673315-B1 POLYETHYLENE FILMS EQUISTAR CHEM LP (US) 2019-03-20 EP disclosed
EP-1943281-B1 HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE BASELL POLYOLEFINE GMBH (DE) 2017-09-20 EP disclosed
US-9676971-B2 Systems, methods and compositions for production of tie-layer adhesives EQUISTAR CHEMICALS, LP (US) 2017-06-13 US disclosed
US-20160222257-A1 SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES EQUISTAR CHEMICALS, LP (US) 2016-08-04 US disclosed
US-9029478-B2 High clarity polyethylene films EQUISTAR CHEMICALS, LP (US) 2015-05-12 US disclosed
EP-2114567-B1 IRON COMPLEXES AND THEIR USE IN POLYMERIZATION PROCESSES BASELL POLYOLEFINE GMBH (DE) 2015-04-15 EP disclosed
US-8865834-B2 Adhesive polymer composition BASELL POLYOLEFINE GMBH (DE) 2014-10-21 US disclosed
US-8722833-B2 Multimodal polyethylene composition, mixed catalyst and process for preparing the composition BASELL POLYOLEFINE GMBH (DE) 2014-05-13 US disclosed
US-8633125-B2 Catalyst composition for preparation of polyethylene BASELL POLYOLEFINE GMBH (DE) 2014-01-21 US disclosed
EP-1753794-B8 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION BASELL POLYOLEFINE GMBH (DE) 2008-07-16 EP disclosed
EP-1943281-A1 HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE Basell Polyolefine GmbH (DE) 2008-07-16 EP disclosed
EP-1753794-B1 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION BASELL POLYOLEFINE GMBH (DE) 2008-06-04 EP disclosed
US-20070255033-A1 Polyethylene for Injection Moldings BASELL POYOLEFINE GMBH (DE) 2007-11-01 US disclosed
US-20070213205-A1 Polyethylene and Catalyst Composition for its Preparation BASELL POLYOLEFINE GMBH (DE) 2007-09-13 US disclosed
WO-2007042252-A1 HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE BASELL POLYOLEFINE GMBH (DE) 2007-04-19 WO disclosed
EP-1753794-A1 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION Basell Polyolefine GmbH (DE) 2007-02-21 EP disclosed
EP-1740623-A1 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION Basell Polyolefine GmbH (DE) 2007-01-10 EP disclosed
WO-2005103100-A1 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION BASELL POLYOLEFINE GMBH (DE) 2005-11-03 WO disclosed
WO-2005103095-A1 POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION BASELL POLYOLEFINE GMBH (DE) 2005-11-03 WO disclosed