Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 15/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189901 | 0.93 | TLR8 (0.53) | TLR8TLR7KDM4EALDH1A1GAA | |
| SCHEMBL8190040 | 0.92 | TLR8 (0.52) | TLR8TLR7KDM4EALDH1A1GAA | |
| SCHEMBL8190192 | 0.90 | TLR8 (0.45) | TLR8TLR7KDM4E | |
| SCHEMBL8179545 | 0.83 | TLR8 (0.60) | TLR8TLR7KDM4EALDH1A1HPGD | |
| SCHEMBL8188956 | 0.83 | TLR8 (0.53) | TLR8TLR7KDM4EALDH1A1HPGD | |
| SCHEMBL10325963 | 0.83 | TLR8 (0.55) | TLR8TLR7 | |
| SCHEMBL10343434 | 0.82 | TLR8 (0.51) | TLR8TLR7NPSR1 | |
| SCHEMBL7505631 | 0.81 | TLR8 (0.63) | TLR8TLR7ALDH1A1GAA | |
| SCHEMBL7508446 | 0.80 | TLR8 (0.62) | TLR8TLR7 | |
| SCHEMBL7509353 | 0.80 | TLR8 (0.54) | TLR8TLR7KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043238-A | 2-Aminobenzazapine derivatives | PFIZER INC. (US) | 2000-03-28 | — | — | US | disclosed |