Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.77 |
| ▸ | TYR | P14679 | 2/20 | 0.73 |
| ▸ | TTR | P02766 | 1/20 | 0.71 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.67 |
| ▸ | STAT3 | P40763 | 2/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.67 |
| ▸ | RELA | Q04206 | 2/20 | 0.67 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.66 |
| ▸ | TUBB | P07437 | 1/20 | 0.66 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.66 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.66 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.66 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.66 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.66 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4268088 | 0.93 | XDH (0.73) | XDHTYRTTRNFE2L2ALOX5 | |
| SCHEMBL4268082 | 0.93 | XDH (0.73) | XDHTYRTTRNFE2L2ALOX5 | |
| SCHEMBL3437056 | 0.92 | XDH (0.88) | XDHTYRTTRNFE2L2ALOX5 | |
| SCHEMBL17732299 | 0.90 | TTR (0.85) | XDHTYRTTRNFE2L2ALOX5 | |
| SCHEMBL30807100 | 0.90 | TTR (0.85) | XDHTYRTTRNFE2L2ALOX5 | |
| SCHEMBL671150 | 0.90 | TTR (0.85) | XDHTYRTTRNFE2L2ALOX5 | |
| SCHEMBL671149 | 0.90 | TTR (0.85) | XDHTYRTTRNFE2L2ALOX5 | |
| SCHEMBL4257517 | 0.89 | TYR (0.74) | XDHTYRTTRNFE2L2ALOX5 | |
| SCHEMBL4257519 | 0.89 | TYR (0.74) | XDHTYRTTRNFE2L2ALOX5 | |
| SCHEMBL8525744 | 0.88 | XDH (0.67) | XDHTYRTTRNFE2L2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11166891-B2 | Bis phenyl hexa trien derivatives, preparation method thereof, and composition for skin whitening containing the same as an active ingredient | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2021-11-09 | — | — | US | disclosed |
| US-11166891-B2 | Bis phenyl hexa trien derivatives, preparation method thereof, and composition for skin whitening containing the same as an active ingredient | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2021-11-09 | — | — | US | disclosed |
| US-20200078279-A1 | BIS PHENYL HEXA TRIEN DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR SKIN WHITENING CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KP) | 2020-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11166891-B2 | Bis phenyl hexa trien derivatives, preparation method thereof, and composition for skin whitening containing the same as an active ingredient | TYR, MITF, TPH1 | XDH 410/4885TYR 1/4885TTR 614/4885 |
| US-20200078279-A1 | BIS PHENYL HEXA TRIEN DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR SKIN WHITENING CONTAINING THE SAME AS AN ACTIVE INGREDIENT | TYR, MITF, TPH1 | XDH 410/4885TYR 1/4885TTR 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.