Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181631 | 0.89 | CYP1A2 (0.45) | LMNAATMPRMT3NPC1SMN1; SMN2 | |
| SCHEMBL13428568 | 0.87 | HPGD (0.40) | LMNAATMPRMT3HTTNPC1 | |
| SCHEMBL8179191 | 0.81 | RAB9A (0.34) | NPC1SMN1; SMN2RARBALDH1A1KMT2A | |
| SCHEMBL8185542 | 0.80 | EPHX2 (0.40) | LMNAPRMT3NPC1EPHX2ALDH1A1 | |
| SCHEMBL13429153 | 0.77 | CYP1A2 (0.45) | LMNANPC1SMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL13428482 | 0.73 | LMNA (0.45) | LMNAPRMT3NPC1SMN1; SMN2EPHX2 | |
| SCHEMBL4215301 | 0.71 | RAB9A (0.40) | RARBALDH1A1KMT2A | |
| SCHEMBL4215307 | 0.71 | RAB9A (0.40) | RARBALDH1A1KMT2A | |
| SCHEMBL13428499 | 0.69 | P2RX3 (0.35) | LMNANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL8179189 | 0.69 | RAB9A (0.39) | HTTNPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075757-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2008-06-26 | — | — | WO | disclosed |