Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413298 | 0.76 | ELANE (0.46) | ELANEHTTGAARAB9A | |
| SCHEMBL5648102 | 0.69 | KDM4E (0.34) | KDM4EALDH1A1ELANEHTTNCOA1 | |
| SCHEMBL28171551 | 0.67 | PER2 (0.32) | ALDH1A1 | |
| SCHEMBL7767003 | 0.67 | KDM4E (0.40) | KDM4EALDH1A1ELANEHTTNCOA1 | |
| SCHEMBL9985612 | 0.66 | ALDH1A1 (0.47) | ALDH1A1LMNA | |
| SCHEMBL13485270 | 0.66 | CYP1A2 (0.43) | KDM4EALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL5640189 | 0.65 | GAA (0.44) | GAA | |
| SCHEMBL5638007 | 0.65 | GAA (0.44) | GAA | |
| SCHEMBL6618485 | 0.65 | CCR2 (0.55) | KDM4EALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL6618482 | 0.65 | CCR2 (0.55) | KDM4EALDH1A1HTTNCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018770-A1 | PYRROLOPYRROLONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXO GROUP LIMITED (GB) | 2000-04-06 | — | — | WO | disclosed |