Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 12/20 | 0.44 |
| ▸ | TCF7L2 | Q9NQB0 | 12/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171027 | 0.92 | SMN1; SMN2 (0.48) | KDM4ECTNNB1TCF7L2GAARXFP1 | |
| SCHEMBL8172354 | 0.91 | PDE4A (0.46) | KDM4EPOLBCTNNB1TCF7L2MEN1 | |
| SCHEMBL8182163 | 0.90 | ALDH1A1 (0.49) | KDM4EPOLBCTNNB1TCF7L2MEN1 | |
| SCHEMBL7012724 | 0.89 | GAA (0.45) | KDM4ECTNNB1TCF7L2GAARXFP1 | |
| SCHEMBL8180295 | 0.87 | PDE4A (0.49) | KDM4ECTNNB1TCF7L2GAARXFP1 | |
| SCHEMBL8171920 | 0.85 | CTNNB1 (0.46) | KDM4EPOLBCTNNB1TCF7L2MEN1 | |
| SCHEMBL8179618 | 0.85 | PDE4A (0.44) | KDM4EGAARXFP1PDE4APDE4B | |
| SCHEMBL7017513 | 0.85 | KDM4E (0.48) | KDM4ECTNNB1TCF7L2KMT2AGAA | |
| SCHEMBL8179286 | 0.85 | PDE4A (0.57) | KDM4EPOLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL8177034 | 0.85 | PDE4A (0.64) | KDM4EPOLBCTNNB1TCF7L2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130223-A | Thienopyrimidine with phosphodiesterase V inhibiting effect | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-10-10 | — | — | US | disclosed |