Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077617 | 0.80 | ATR (0.38) | ALOX15BACE1ATRIDO1SRC | |
| SCHEMBL8171638 | 0.77 | BACE1 (0.38) | ALOX15BACE1ATRIDO1SRC | |
| SCHEMBL2244599 | 0.74 | ATR (0.40) | ALOX15BACE1ATRIDO1SRC | |
| SCHEMBL5468578 | 0.73 | ATR (0.38) | ALOX15BACE1ATRIDO1SRC | |
| SCHEMBL2296526 | 0.73 | ATR (0.36) | ALOX15BACE1ATRSRCCXCR2 | |
| SCHEMBL2662890 | 0.70 | CA2 (0.38) | IDO1ADORA2AMPO | |
| SCHEMBL5468582 | 0.70 | ATR (0.38) | ALOX15BACE1ATRIDO1SRC | |
| SCHEMBL14417244 | 0.69 | IDO1 (0.34) | ALOX15IDO1MPO | |
| SCHEMBL2999349 | 0.69 | ADORA3 (0.46) | ADORA2AMAOB | |
| SCHEMBL19139129 | 0.68 | IDO1 (0.31) | IDO1MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165943-A | Thiazolimine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-26 | — | — | US | disclosed |