Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.69 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.60 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181654 | 1.00 | KDR (0.69) | KDRSLC2A1MAPTMEN1KMT2A | |
| SCHEMBL10492212 | 0.87 | POLB (0.75) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL10492218 | 0.87 | POLB (0.75) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL13056337 | 0.87 | POLB (0.75) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL8172936 | 0.85 | MAPT (0.64) | KDRMAPTMEN1KMT2APOLB | |
| SCHEMBL13186618 | 0.85 | MEN1 (0.62) | KDRSLC2A1MAPTMEN1KMT2A | |
| SCHEMBL29214843 | 0.83 | MAPT (0.72) | KDRSLC2A1MAPTMEN1KMT2A | |
| SCHEMBL29214838 | 0.83 | MAPT (0.72) | KDRSLC2A1MAPTMEN1KMT2A | |
| SCHEMBL9011343 | 0.79 | AKR1B1 (0.84) | MAPTAKR1B1CA9 | |
| SCHEMBL9011346 | 0.79 | AKR1B1 (0.84) | MAPTAKR1B1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018746-A1 | THIAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |