Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817659 | 0.89 | TSHR (0.56) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL818412 | 0.87 | TSHR (0.57) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL818613 | 0.86 | TSHR (0.58) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL819237 | 0.84 | TSHR (0.50) | ALDH1A1LMNATSHRESR1L3MBTL1 | |
| SCHEMBL818396 | 0.80 | ALDH1A1 (0.45) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL21592197 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL18892777 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL818618 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL817653 | 0.76 | TSHR (0.55) | ALDH1A1TSHRTDP1CHRM1L3MBTL1 | |
| SCHEMBL818415 | 0.75 | ALDH1A1 (0.44) | ALDH1A1LMNATSHRTDP1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |