Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819205 | 0.82 | ALDH1A1 (0.47) | TSHRALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL819237 | 0.79 | TSHR (0.50) | TSHRALDH1A1MAPTHTTKDM4E | |
| SCHEMBL818845 | 0.76 | TSHR (0.49) | TSHRALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL818805 | 0.76 | ALDH1A1 (0.45) | TSHRALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL818173 | 0.76 | ALDH1A1 (0.53) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL819067 | 0.75 | ALDH1A1 (0.63) | TSHRALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL817677 | 0.75 | CA12 (0.42) | TSHRALDH1A1NPC1RAB9AHTT | |
| SCHEMBL827863 | 0.74 | TSHR (0.70) | TSHRALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL816941 | 0.74 | ALDH1A1 (0.43) | TSHRALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL817659 | 0.73 | TSHR (0.56) | TSHRALDH1A1SMN1; SMN2TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |