Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819433 | 0.78 | GAA (0.40) | ALDH1A1KDM4EHPGDMAPTHTT | |
| SCHEMBL819174 | 0.77 | KDM4E (0.37) | ALDH1A1KDM4EMAPTHSD17B10LMNA | |
| SCHEMBL818754 | 0.74 | TSHR (0.38) | KCNH2ALDH1A1KDM4EHPGDATM | |
| SCHEMBL817269 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTHTTTSHR | |
| SCHEMBL818110 | 0.73 | L3MBTL1 (0.41) | ALDH1A1KDM4EHPGDATMCYP1A2 | |
| SCHEMBL817755 | 0.73 | TSHR (0.42) | ALDH1A1HPGDATMMAPTTSHR | |
| SCHEMBL817763 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTTSHRHSD17B10 | |
| SCHEMBL31174918 | 0.71 | KCNH2 (0.41) | KCNH2ALDH1A1KDM4EHPGDATM | |
| SCHEMBL818458 | 0.71 | KCNH2 (0.38) | KCNH2ALDH1A1KDM4EHPGDATM | |
| SCHEMBL13671086 | 0.70 | KCNH2 (0.40) | KCNH2ALDH1A1KDM4EHPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |