Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817658 | 0.83 | CA12 (0.40) | TSHRALDH1A1RAB9AHTTMAPT | |
| SCHEMBL817535 | 0.80 | ALDH1A1 (0.41) | TSHRALDH1A1NPC1RAB9AHTT | |
| SCHEMBL818399 | 0.80 | CA12 (0.40) | TSHRALDH1A1HTTMAPTTDP1 | |
| SCHEMBL818249 | 0.78 | TSHR (0.44) | TSHRALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL818118 | 0.77 | CRHBP (0.35) | TSHRALDH1A1TDP1NPSR1 | |
| SCHEMBL819104 | 0.74 | ALDH1A1 (0.47) | TSHRALDH1A1PLA2G1BATG4BNPC1 | |
| SCHEMBL819445 | 0.71 | ALDH1A1 (0.44) | TSHRALDH1A1PLA2G1BATG4BNPC1 | |
| SCHEMBL818845 | 0.69 | TSHR (0.49) | TSHRALDH1A1PLA2G1BATG4BNPC1 | |
| SCHEMBL818063 | 0.69 | ALDH1A1 (0.41) | TSHRALDH1A1PLA2G1BATG4BNPC1 | |
| SCHEMBL818206 | 0.68 | TSHR (0.47) | TSHRALDH1A1PLA2G1BATG4BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |