SCHEMBL455573

SCHEMBL455573

O=C(O)c1c2nc(c(-c3ccccc3)c3ccc(cc4nc(cc5ccc1[nH]5)C=C4)[nH]3)C=C2

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.67
▸ STAT1 P42224 1/20 0.67
▸ TOP1 P11387 4/20 0.50
▸ CYCS P99999 4/20 0.49
▸ ABCG2 Q9UNQ0 1/20 0.40
▸ ENPP2 Q13822 1/20 0.40
▸ TERT O14746 3/20 0.36
▸ DHODH Q02127 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ GFER P55789 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8977875 0.96 STAT3 (0.69) STAT3STAT1TOP1CYCSABCG2
SCHEMBL6291665 0.90 STAT3 (0.62) STAT3STAT1TOP1CYCSABCG2
SCHEMBL226835 0.89 STAT3 (0.83) STAT3STAT1TOP1CYCSABCG2
SCHEMBL29585686 0.89 STAT3 (0.83) STAT3STAT1TOP1CYCSABCG2
SCHEMBL5034725 0.89 STAT3 (0.47) STAT3STAT1TOP1CYCSABCG2
SCHEMBL1224432 0.85 STAT3 (0.86) STAT3STAT1TOP1CYCSABCG2
SCHEMBL31550992 0.85 STAT3 (0.86) STAT3STAT1TOP1CYCSABCG2
SCHEMBL30293296 0.85 STAT3 (0.86) STAT3STAT1TOP1CYCSABCG2
SCHEMBL473158 0.85 STAT3 (0.86) STAT3STAT1TOP1CYCSABCG2
SCHEMBL30753635 0.85 STAT3 (0.86) STAT3STAT1TOP1CYCSABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12461102-B2 Pristine graphene based biosensor for biomarker detection and related core particles, materials compositions methods and systems HAWKEYE BIO, LIMITED (IE) 2025-11-04 — — US claimed
WO-2024010609-A1 PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS HAWKEYE BIO, LIMITED (IE) 2024-01-11 — — WO claimed
EP-4271651-A1 PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS HAWKEYE BIO, LIMITED (IE) 2023-11-08 — — EP claimed
WO-2022147171-A1 PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS HAWKEYE BIO, LIMITED (US) 2022-07-07 — — WO claimed
WO-2016018798-A1 NANOSENSORS FOR DETECTING ENZYMATIC ACTIVITY IN DAIRY PRODUCTION KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2016-02-04 — — WO claimed
US-8969027-B2 Protease assay KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2015-03-03 — — US claimed
EP-2473620-A2 MRI AND OPTICAL ASSAYS FOR PROTEASES Kansas State University Research Foundation (US) 2012-07-11 — — EP claimed
JP-2011517934-A — — 2011-06-23 — — JP claimed
WO-2011028698-A2 MRI AND OPTICAL ASSAYS FOR PROTEASES KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-03-10 — — WO claimed
US-20110014125-A1 PROTEASE ASSAY KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-01-20 — — US claimed
EP-2260108-A2 PROTEASE ASSAY Kansas State University Research Foundation (US) 2010-12-15 — — EP claimed
WO-2009111470-A2 PROTEASE ASSAY KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2009-09-11 — — WO claimed
US-12461102-B2 Pristine graphene based biosensor for biomarker detection and related core particles, materials compositions methods and systems HAWKEYE BIO, LIMITED (IE) 2025-11-04 — — US disclosed
EP-4271651-B1 PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS HAWKEYE BIO LTD (IE) 2024-10-23 — — EP disclosed
US-11965881-B2 Nanosensors and methods for detection of biological markers KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2024-04-23 — — US disclosed
US-20240125800-A1 NANOSENSORS FOR RAPID IDENTIFICATION OF LUNG CONDITIONS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2024-04-18 — — US disclosed
US-4749642-A NO WATER WASHING STEP KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-06-07 — — US disclosed
EP-0186169-A2 Method for processing of light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1986-07-02 — — EP disclosed
EP-0070686-B1 NON-RADIATIVE ENERGY TRANSFER IMMUNOCHEMICAL TECHNIQUE AMOCO CORPORATION (US) 1985-10-02 — — EP disclosed
EP-0070686-A2 Non-radiative energy transfer immunochemical technique AMOCO CORPORATION (US) 1983-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110014125-A1 PROTEASE ASSAY PREP, TMPRSS15, PRSS3 STAT3 1701/4885STAT1 3069/4885TOP1 3563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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