Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.55 |
| ▸ | ITGAV | P06756 | 3/20 | 0.47 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | PLG | P00747 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27464968 | 0.87 | ITGB3 (0.64) | ITGB3ITGA2BITGAVF2PLAU | |
| SCHEMBL7753614 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BITGAVF10F2 | |
| SCHEMBL27462389 | 0.86 | ITGB3 (0.63) | ITGB3ITGA2BITGAVF2PLAU | |
| SCHEMBL8185232 | 0.86 | ITGB3 (0.63) | ITGB3ITGA2BITGAVF2PLAU | |
| SCHEMBL8175245 | 0.86 | ITGB3 (0.48) | ITGB3ITGA2BF2 | |
| SCHEMBL7753440 | 0.85 | ITGB3 (0.62) | ITGB3ITGA2BITGAVF10PLG | |
| SCHEMBL8198202 | 0.85 | ITGB3 (0.62) | ITGB3ITGA2BITGAVF10PLG | |
| SCHEMBL8185170 | 0.81 | ITGB3 (0.54) | ITGB3ITGA2BITGAVF2PLAU | |
| SCHEMBL8188715 | 0.79 | ITGB3 (0.51) | ITGB3ITGA2BITGAV | |
| SCHEMBL8185293 | 0.79 | ITGB3 (0.50) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |