Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.63 |
| ▸ | ITGAV | P06756 | 3/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | HPN | P05981 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27462389 | 1.00 | ITGB3 (0.63) | ITGB3ITGA2BITGAVF2TMPRSS6 | |
| SCHEMBL27464968 | 0.99 | ITGB3 (0.64) | ITGB3ITGA2BITGAVF2TMPRSS6 | |
| SCHEMBL8185170 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BITGAVF2TMPRSS6 | |
| SCHEMBL7748728 | 0.89 | ITGB3 (0.60) | ITGB3ITGA2BITGAVF2TMPRSS6 | |
| SCHEMBL27543479 | 0.89 | ITGB3 (0.60) | ITGB3ITGA2BITGAVF2TMPRSS6 | |
| SCHEMBL8189053 | 0.88 | MMP2 (0.52) | ITGB3ITGA2BITGAVPLAUHPN | |
| SCHEMBL8185091 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2BITGAVF2PLAU | |
| SCHEMBL27489722 | 0.85 | ITGB3 (0.67) | ITGB3ITGA2BITGAV | |
| SCHEMBL7753368 | 0.85 | ITGB3 (0.67) | ITGB3ITGA2BITGAV | |
| SCHEMBL8175245 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BF2TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |