SCHEMBL3209247

SCHEMBL3209247

O=C(CF)C(F)(F)c1cccc2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ACP3 P15309 2/20 0.42
KIF11 P52732 1/20 0.40
TDP1 Q9NUW8 2/20 0.40
CNR2 P34972 1/20 0.39
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39
NR4A3 Q92570 1/20 0.39
PTPN1 P18031 1/20 0.39
PTPRC P08575 1/20 0.38
ABCC9 O60706 3/20 0.38
ABCC8 Q09428 3/20 0.38
KCNJ11 Q14654 3/20 0.38
KCNJ8 Q15842 3/20 0.38
TRPV1 Q8NER1 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1720994 0.83 KDM4E (0.43) KDM4EMEN1KMT2AACP3KIF11
SCHEMBL8185296 0.80 KDM4E (0.49) KDM4EMEN1KMT2AACP3KIF11
SCHEMBL30707929 0.80 KDM4E (0.49) KDM4EMEN1KMT2AACP3KIF11
SCHEMBL28705859 0.79 KDM4E (0.47) KDM4EMEN1KMT2AACP3KIF11
SCHEMBL16147542 0.76 ACP3 (0.60) KDM4EMEN1KMT2AACP3KIF11
SCHEMBL17289035 0.76 KDM4E (0.44) KDM4EMEN1KMT2AACP3KIF11
SCHEMBL27176541 0.74 ALDH1A1 (0.49) KDM4EMEN1KMT2ATDP1ABCC9
SCHEMBL710253 0.73 NR4A1 (0.49) KDM4EMEN1KMT2ATDP1CNR2
SCHEMBL10570998 0.73 KDM4E (0.41) KDM4EMEN1KMT2AACP3KIF11
SCHEMBL29035967 0.71 KDM4E (0.47) KDM4EMEN1KMT2AACP3KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100044639-A1 STABILIZED CORE-SHELL NANOPARTICLES OF HYDROPHOBIC METAL COMPLEXES AND REPRECIPATION-ENCAPSULATION METHOD FOR PREPARING SAME NATIONAL SCIENCE FOUNDATION 2010-02-25 US claimed
CN-1575327-A Europium-ammonium tetra chelates HONEYWELL INT INC (US) 2005-02-02 CN claimed
US-6030840-A CONTACTING CHELATED LANTHANIDE METAL IONS BOUND TO MARKER WITH BUFFERED SOLUTION OF DETERGENT, ENHANCER REAGENT AND POLYANION; IONS DISSOCIATE FROM MARKER AND REASSOCIATE WITH ENHANCER; THEN DETERMINING AMOUNT OF IONS LIBERATED NEN LIFE SCIENCES, INC. (US) 2000-02-29 US claimed
WO-1999066333-A1 NEUTRAL ENHANCEMENT OF LANTHANIDES FOR TIME RESOLVED FLUORESCENCE NEN LIFE SCIENCE PRODUCTS, INC. (US) 1999-12-23 WO claimed
US-20100044639-A1 STABILIZED CORE-SHELL NANOPARTICLES OF HYDROPHOBIC METAL COMPLEXES AND REPRECIPATION-ENCAPSULATION METHOD FOR PREPARING SAME NATIONAL SCIENCE FOUNDATION 2010-02-25 US disclosed
CN-1788072-A Caustic high-foam contact detergent JOHNSON DIVERSEY INC (US) 2006-06-14 CN disclosed
US-20050194885-A1 Red emission organic phosphor with broad excitation band AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2005-09-08 US disclosed
CN-1575327-A Europium-ammonium tetra chelates HONEYWELL INT INC (US) 2005-02-02 CN disclosed
US-6030840-A CONTACTING CHELATED LANTHANIDE METAL IONS BOUND TO MARKER WITH BUFFERED SOLUTION OF DETERGENT, ENHANCER REAGENT AND POLYANION; IONS DISSOCIATE FROM MARKER AND REASSOCIATE WITH ENHANCER; THEN DETERMINING AMOUNT OF IONS LIBERATED NEN LIFE SCIENCES, INC. (US) 2000-02-29 US disclosed
WO-1999066333-A1 NEUTRAL ENHANCEMENT OF LANTHANIDES FOR TIME RESOLVED FLUORESCENCE NEN LIFE SCIENCE PRODUCTS, INC. (US) 1999-12-23 WO disclosed