Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750354 | 0.89 | GAA (0.35) | LMNANPSR1MAPTSTAT1RAB9A | |
| SCHEMBL5772424 | 0.78 | LMNA (0.49) | LMNANPSR1MAPTSTAT1RAB9A | |
| SCHEMBL13228906 | 0.69 | NPSR1 (0.44) | LMNANPSR1MAPTSTAT1RAB9A | |
| SCHEMBL8686608 | 0.68 | LMNA (0.38) | LMNANPSR1MEN1GAATSHR | |
| SCHEMBL7668283 | 0.68 | NPSR1 (0.43) | LMNANPSR1MAPTSTAT1RAB9A | |
| SCHEMBL9393408 | 0.67 | CYP1A2 (0.46) | LMNANPSR1MEN1GAATSHR | |
| SCHEMBL9423133 | 0.66 | TSHR (0.47) | LMNANPSR1MAPTSTAT1RAB9A | |
| SCHEMBL18210830 | 0.66 | HSD17B10 (0.58) | LMNANPSR1MAPTRAB9AMEN1 | |
| SCHEMBL891106 | 0.65 | NPSR1 (0.54) | LMNANPSR1MAPTSTAT1RAB9A | |
| SCHEMBL8686610 | 0.64 | NPSR1 (0.38) | LMNANPSR1MAPTSTAT1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022981-A | KEY INTERMEDIATES IN SYNTHESIZING 5,10-DISUBSTITUTED PORPHYRIN COMPOUNDS OR OTHER 5,10-DISUBSTITUTED POLYPYRROLIC MACROCYCLES. | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2000-02-08 | — | — | US | disclosed |
| US-5919923-A | REACTING ALDEHYDE OR ACETAL WITH STOICHIOMETRIC EXCESS OF PYRROLE IN PRESENCE OF ACID CATALYST, REMOVING SOLVENT BY EVAPORATION TO FORM RESIDUE, REMOVING HIGH MOLECULAR WEIGHT BY-PRODUCTS TO LEAVE DESIRED TRIPYRRANE | BRITISH COLUMBIA, UNIVERSITY OF, THE (CA) | 1999-07-06 | — | — | US | disclosed |